LDH
- 1 lab in 1 country
- Funders: National Institute of General Medical Sciences and 3 more
- Humans1
- Model organisms4
Effects
3Lipid-droplet
upin flies1
1 study
Lipid-droplet
upin flies1
LDH increases lipid-droplet in flies.
“Both neuronal and glial dLdh upregulation increased neutral lipid accumulation.”
Model organismsneuronal and glial upregulationbrain
Aging
Long-term courtship memory
downin flies1
1 study
Long-term courtship memory
downin flies1
LDH impairs long-term courtship memory in flies.
“Both upregulation and downregulation of dLdh in neurons resulted in decreased survival and memory impairment with age.”
Model organismsupregulation or downregulation in neuronsbrain
Aging
Survival
downin flies1
1 study
Survival
downin flies1
LDH shortens lifespan survival in flies.
“Both upregulation and downregulation of dLdh in neurons resulted in decreased survival and memory impairment with age.”
Model organismsupregulation or downregulation in neuronsbrain
Aging
Funding
1 grant since 2023Japan Society for the Promotion of ScienceJP¥2.9m
Latest
1 paper in 12 monthsScience Progress
Endothelial dysfunction and long-term survival in cardiovascular-kidney-metabolic syndrome stages 0-3: An EASIX-based national cohort study
Cohort study of 10,885 peopleEndothelial dysfunction
bioRxiv
Alzheimer’s disease risk gene Wwox protects against amyloid pathology through metabolic reprogramming
Preprint: experiments in fliesMethionine and one-carbon metabolism