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ImpL2

Gene

1 paper3 findings

Taxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Against: findings that point the other way from most findings on the same outcome.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • 1 finding against
  • Model organisms1

Effects

2

Lifespan

downin flies1upin flies1

1 study

  1. ImpL2 shortens lifespan in flies.

    “germline-specific knockdown of Imp-L2 shortened the lifespan of female flies”

    Model organismsgermline-specific knockdownfemales

    Germline expression of Imp-L2 in Drosophila females enhances reproductive activity and longevity

    Animal cells and systemsMar 17, 2025

  2. ImpL2 extends lifespan in flies.

    “whereas its overexpression extended it”

    Model organismsfemales

    Germline expression of Imp-L2 in Drosophila females enhances reproductive activity and longevity

    Animal cells and systemsMar 17, 2025

Fecundity

upin flies1

1 study

  1. ImpL2 improves fecundity in flies.

    “Imp-L2 expression in the germline promotes both reproductive activity and longevity”

    Model organismsfemales

    Germline expression of Imp-L2 in Drosophila females enhances reproductive activity and longevity

    Animal cells and systemsMar 17, 2025

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