HIF3A

Gene2 papers2 findingsHGNC 15825NCBI Gene 64344Taxon 9606

Humans1
Animals1

Effects

1

BNIP3

upin mice1

1 study

HIF3A increases BNIP3 in mice.
Animalsin senescent cardiomyocytes
Mitochondrial Transplantation Rejuvenates Aging Heart by Restoring Mitophagy Flux via the HIF-3α-BNIP3 Axis · Aging cell · 23 Sep 2026

Upstream

1

Alzheimer's disease

downin humans1

1 study

Alzheimer's disease decreases HIF3A in humans.
Humansin AD hippocampus vulnerable regions (CA1, CA2)hippocampus
HIF-2α Depletion and HIF-1α Overexpression in Vulnerable Brain Regions Distinguish Alzheimer's Disease with Cerebral Amyloid Angiopathy · International journal of molecular sciences · 31 Aug 2026

Alzheimer's disease →

Latest

2

Aging CellAnimals23 Sep

Mitochondrial Transplantation Rejuvenates Aging Heart by Restoring Mitophagy Flux via the HIF-3α-BNIP3 Axis

International Journal of Molecular SciencesHumans15 Sep

HIF-2α Depletion and HIF-1α Overexpression in Vulnerable Brain Regions Distinguish Alzheimer's Disease with Cerebral Amyloid Angiopathy