GENETICVARIANTS

1. GENETICVARIANTS is associated with age-specific blood pressure changes in humans (127 independent loci).

   “we identify 127 independent loci associated with age-specific BP changes later in life”

   Humansn = 211,845

   Separating the genetics of disease, treatment, and treatment response using graphical modeling and large-scale electronic health records

   medRxiv : the preprint server for health sciences·Mar 20, 2026Preprint

1. GENETICVARIANTS is associated with physical and biochemical traits in humans (533 independent loci).

   “In total, 533 independent loci reach Bonferroni significance after clumping.”

   Humansn = 50,000

   The Taizhou Longitudinal Study: a population-based biobank resource of genetic and biochemical biomarkers for precision medicine in China

   Journal of genetics and genomics = Yi chuan xue bao·Feb 7, 2026

1. GENETICVARIANTS is associated with frailty in humans (15 SNPs (P < .001); 18 genes (P < .005)).

   “We found 15 SNPs (P < .001), 18 genes (P < .005), and 4 pathways (P < .05)”

   Humans

   Relation Between Genetic Factors and Frailty in Older Adults

   Journal of the American Medical Directors Association·May 8, 2019

1. GENETICVARIANTS is associated with red blood cell distribution width in humans (29% (33.8% in 60+ year olds, 28.4% in <50 year olds)).

   “A large proportion RDW is explained by genetic variants (29%), especially in the older group”

   Humansn = 116,666

   Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers

   PloS one·Sep 28, 2017

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