GBP2

1. GBP2 decreases endothelial tube formation in human cells.

   “The endothelial cells with elevated Gbp2 expression displayed compromised tube formation.”

   CellsGBP2 overexpressionhuman umbilical vein endothelial cell

   Single-cell RNA-seq reveals interferon-induced guanylate-binding proteins are linked with sarcopenia

   Journal of cachexia, sarcopenia and muscle·Sep 26, 2022

1. GBP2 lowers the risk of cholangiocarcinoma in silico (OR = 0.548, p = 0.001).

   “protective against cholangiocarcinoma (OR = 0.548, p = 0.001)”

   In silicoliver

   Causal Effects of a Hepatic Senescence Gene Set on MASLD Fibrosis: A Mendelian Randomization Study and Quercetin Molecular Docking Analysis

   Biomedicines·Mar 17, 2026

More on Cholangiocarcinoma

1. GBP2 raises the risk of liver fibrosis in silico (OR = 1.904, p = 0.028).

   “MR analysis identified elevated GBP2 expression as a risk factor for liver fibrosis (OR = 1.904, p = 0.028)”

   In silicoliver

   Causal Effects of a Hepatic Senescence Gene Set on MASLD Fibrosis: A Mendelian Randomization Study and Quercetin Molecular Docking Analysis

   Biomedicines·Mar 17, 2026

More on Liver fibrosis