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G3PPHOSPHATASE

Gene

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Agence Nationale de la Recherche and 2 more
  • 1 of 1 finding with company ties
  • Cells1

Effects

1

Cellular senescence

downin human cells1

1 study

  1. G3PPHOSPHATASE decreases cellular senescence in human cells.

    “G3P phosphatase and ethanolamine-phosphate phospho-lyase-based scavenging of G3P and pEtN acts in a senomorphic way by reducing G3P and pEtN accumulation”

    Cellsscavenging of G3P and pEtNfibroblasts

    A homoeostatic switch causing glycerol-3-phosphate and phosphoethanolamine accumulation triggers senescence by rewiring lipid metabolism

    Nature metabolism19 Feb 2024

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