crq

Gene

1 paper2 findings

NCBI GeneTaxon

  • 1 lab in 1 country
  • Funders: National Institute of Neurological Disorders and Stroke and 1 more
  • Model organisms1

Effects

2

Age-related synaptic loss

downin flies1

1 study
  1. crq prevents age-related synaptic loss in flies.

    “Loss of Crq in glia also prevents age-related synaptic, but not neuronal, loss in the adult brain.”

    Model organismsloss of Crq in gliabrain

    Developmental and age-related synapse elimination is mediated by glial Croquemort

    Neuron8 Jun 2026

Seizure susceptibility

upin flies1

1 study
  1. crq increases seizure susceptibility in flies.

    “glial Crq loss leading to excess CNS synapses and progressive seizure susceptibility in adults.”

    Model organismsloss of glial Crq

    Developmental and age-related synapse elimination is mediated by glial Croquemort

    Neuron8 Jun 2026

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