Cirl

1 paper1 finding

NCBI Gene Taxon

1 lab in 1 country

Funder: American Lebanese Syrian Associated Charities

Model organisms1

Effects

1

huntingtin-polyQ protein aggregates

upin flies1

1 study

Cirl increases huntingtin-polyQ protein aggregates in flies.
“pathogenic polyglutamine aggregates are reduced by knockdown of the lectin domain-containing G-protein coupled receptor Cirl”
Model organismsshown by knockdown
Regulation of huntingtin-polyQ aggregation by glucose transporters and saccharide-binding receptors during aging in Drosophila
The journals of gerontology. Series A, Biological sciences and medical sciences6 Jun 2026

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The Journals of Gerontology, Series A6 Jun

Regulation of huntingtin-polyQ aggregation by glucose transporters and saccharide-binding receptors during aging in Drosophila

Experiments in fliesMechanisms