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chd-7

Gene

1 paper studies it2 findings

Taxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Consejo Nacional de Investigaciones Científicas y Técnicas and 4 more
  • Model organisms1

Effects

2

daf-9

downin worms1

1 study

  1. chd-7 inhibits daf-9 in worms.

    “Transcriptomic analysis revealed that chd-7 mutants fail to repress daf-9 for execution of the dauer program.”

    Model organismsin chd-7 mutants

    The CHARGE syndrome ortholog CHD-7 regulates TGF-β pathways in Caenorhabditis elegans

    Proceedings of the National Academy of Sciences of the United States of America

More on daf-9

Lifespan

is required forin worms1

1 study

  1. chd-7 is required for lifespan in worms.

    “chd-7, the nematode ortholog of Chd7, is required for dauer morphogenesis, lifespan determination, stress response, and body size determination.”

    Model organismsin chd-7 mutants

    The CHARGE syndrome ortholog CHD-7 regulates TGF-β pathways in Caenorhabditis elegans

    Proceedings of the National Academy of Sciences of the United States of America

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