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CENPC

Gene

1 paper studies it2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Centre National de la Recherche Scientifique and 5 more
  • Animals1

Effects

2

Chromosome alignment

upin mice1

1 study

  1. CENPC improves chromosome alignment in mice.

    “This intervention also partially improves chromosome alignment in oocytes from older animals.”

    AnimalsExogenous CENP-C expressionoocytefemales

    Weaker chromosome anchors linked to errors in mouse egg cells

    The Journal of cell biology

Chromosome segregation errors

downin mice1

1 study

  1. CENPC decreases chromosome segregation errors in mice.

    “The expression of exogenous CENP-C rescues these defects via CENP-B-dependent centromere binding”

    AnimalsExogenous CENP-C expression after acute CENP-A degradationoocytefemales

    Weaker chromosome anchors linked to errors in mouse egg cells

    The Journal of cell biology

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 11 paper in 12 months
The Journal of Cell Biology

Weaker chromosome anchors linked to errors in mouse egg cells

Laboratory experiments found lower levels of two proteins at chromosome attachment sites in older mouse egg cells, alongside changes in the fibers that move chromosomes.Laboratory experiments found lower levels of two proteins at chromosome attachment sites in older mouse egg cells, alongside changes in the fibers that move chromosomes.

Animal cell studyMechanisms
Paper

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