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CANNABINOIDRECEPTOR1

There is 1 paper on CANNABINOIDRECEPTOR1 in aging research: none in people yet, 1 in cells.

Gene

1 paper studies it1 finding

See all 1 papers on CANNABINOIDRECEPTOR1

At a glance

The findings reach cells, none yet in people. 1 lab in 1 country.

Cells: a single group. Worms or flies, mice and humans: nothing yet.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funder: National Natural Science Foundation of China
  • Cells1

Effects

1

Cellular senescence

is required forin human cells1

1 study

  1. CANNABINOIDRECEPTOR1 is required for cellular senescence in human cells (suppression by arachidonyl-2-chloroethylamide, abolished by AM251 antagonism).

    “these functions of agonist arachidonyl-2-chloroethylamide were abolished by the cannabinoid receptor 1 selective antagonist AM251, suggesting the involvement of cannabinoid receptor 1.”

    Cellssuppression by arachidonyl-2-chloroethylamide, abolished by AM251 antagonism

    Activation of the cannabinoid receptor 1 by ACEA suppresses senescence in human primary chondrocytes through sirt1 activation

    Experimental biology and medicine (Maywood, N.J.)

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