There are 4 papers on ARX in aging research: 1 observational study in people, 1 in animals, 2 in cells.
At a glance
The findings reach people, from one lab or study. 1 lab in 1 country.
“Methylation at two CpGs overlapping TMEM49 and ARX genes was associated with survival of overall (HR = 0.91, p = 7.7 × 10−4) and colorectal (HR = 1.52, p = 1.8 × 10−4) cancer”
Humans: a single group. Cells, worms or flies and mice: nothing yet.
- 1 lab in 1 country
- Funders: Cancer Council Victoria and 1 more
- Humans1
- Animals1
- Cells2
Associations
1Colorectal cancer mortality
upin humans1HR 1.52
1 study
Colorectal cancer mortality
upin humans1HR 1.52
ARX is linked with a higher risk of colorectal cancer mortality in humans (colorectal cancer) (HR = 1.52, p = 1.8 × 10−4).
“Methylation at two CpGs overlapping TMEM49 and ARX genes was associated with survival of overall (HR = 0.91, p = 7.7 × 10−4) and colorectal (HR = 1.52, p = 1.8 × 10−4) cancer”
Humanscolorectal cancer
Epigenetic Drift Association with Cancer Risk and Survival, and Modification by Sex
Cancers
Latest
1 paper in 12 monthsThe Journal of Biological Chemistry
The Welander TIA1 mutation dedifferentiates insulin-producing cells: Reversal by a GLP-1 receptor agonist
Experiments in human cellsGLP-1 receptor agonists
The Biochemical Journal
A nexus of miR-1271, PAX4 and ALK/RYK influences the cytoskeletal architectures in Alzheimer's Disease and Type 2 Diabetes
Experiments in cellsMechanisms
Cancers
Epigenetic Drift Association with Cancer Risk and Survival, and Modification by Sex
Case-control study of 869 peopleCancer
Cell Metabolism
Converting Adult Pancreatic Islet α Cells into β Cells by Targeting Both Dnmt1 and Arx
Experiments in miceMechanisms