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ARRDC2

Gene

1 paper1 finding

HGNCNCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: National Institute of Arthritis and Musculoskeletal and Skin Diseases and 3 more
  • Animals1

Interventions

1

Mechanical overload

downin mice1

1 study

  1. Mechanical overload decreases ARRDC2 in mice.

    “Increasing mechanical load beyond normal ambulatory levels lowered Arrdc2 mRNA, but not Arrdc3 mRNA, in young and aged muscle.”

    Animalsincreasing mechanical load beyond normal ambulatory levels

    The mechanosensitive gene arrestin domain containing 2 regulates myotube diameter with direct implications for disuse atrophy with aging

    American journal of physiology. Cell physiology5 Feb 2024

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