alg-3

alg-3 extends lifespan in worms.

“we describe synergistic lifespan extension of insulin/IGF-1 signaling (IIS) mutant age-1(hx546) by rde-4 or alg-3; alg-4 deficiencies”

Model organismsage-1(hx546) mutant background

Mutual regulation of spermatogenesis-specific Argonaute proteins and Insulin/IGF-1 signaling in aging control

EMBO reports·8 Jan 2026