Therapy-related myeloid neoplasms

Disease1 paper

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Nature GeneticsHumans

Germline HRD limits therapy-driven clonal hematopoiesis

Serial blood samples revealed carboplatin and PARP inhibitors expand DNA damage response clones, though germline homologous recombination deficiency…Serial blood samples revealed carboplatin and PARP inhibitors expand DNA damage response clones, though germline homologous recombination deficiency reduces this growth.