PLOS Pathogens
Older cotton rats showed weaker responses to a respiratory virus
An experiment in six-animal groups found weaker inflammation-related lung gene activity in older cotton rats one and four days after respiratory syncytial virus…An experiment in six-animal groups found weaker inflammation-related lung gene activity in older cotton rats one and four days after respiratory syncytial virus infection.
Animal studyImmune response
Who was studiedGeriatric cotton rats, four days, against adult cotton rats
What changedAfter infection, older cotton rats had lower activity of genes involved in inflammation and a Th1 response than adult rats
The catchGroups had only six animals, and spleen tests included only three geriatric rats