Renal hyperfiltration

1. Renal hyperfiltration decreases estimated glomerular filtration rate in humans (-9.5 to -9.9 mL/min/1.73 m2 (p < 0.001)).

   “those with hyperfiltration experienced an additional annual reduction of -9.5 to -9.9 mL/min/1.73 m2 compared with normal filtration (p < 0.001) over four years follow-up.”

   Humanscompared with participants with normal baseline filtration4 years

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