Rectal cancer

Disease2 papers2 findings

  • Humans2

Associations

2

Smoking

upin humans1Low certainty

1 study
  1. Smoking raises the risk of rectal cancer in humans (aHR 1.23, 95% CI 1.04-1.45).

    “concurrent CC and NNTP use (aHR 1.23, 95% CI 1.04-1.45)”

    Humansconcurrent CC and NNTP use

    Smoking Status, Including Non-Combustible Nicotine or Tobacco Products Use, and Site-Specific Colorectal Cancer Risk: A Nationwide Cohort Study · Cancers · 16 Sep 2026

Smoking →

Non-combustible nicotine or tobacco product

upin humans1Low certainty

1 study
  1. Non-combustible nicotine or tobacco product raises the risk of rectal cancer in humans (aHR 1.51, 95% CI 1.19-1.92).

    “Rectal cancer risk was higher for switching from CCs to NNTPs (aHR 1.51, 95% CI 1.19-1.92)”

    Humansswitching from CCs to NNTPs

    Smoking Status, Including Non-Combustible Nicotine or Tobacco Products Use, and Site-Specific Colorectal Cancer Risk: A Nationwide Cohort Study · Cancers · 16 Sep 2026

Non-combustible nicotine or tobacco product →

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The Lancet Healthy LongevityHumans

Pre-existing dementia tied to higher cancer mortality

Five-year cancer-specific mortality reached 44.0% in cancer patients with dementia compared with 39.4% in matched cancer patients without dementia.Five-year cancer-specific mortality reached 44.0% in cancer patients with dementia compared with 39.4% in matched cancer patients without dementia.