Prediabetes and diabetes

Disease

1 paper2 findings

  • Humans1

Associations

2

Waist-to-height ratio

upin humans1HR 2.9

1 study
  1. Waist-to-height ratio raises the risk of prediabetes and diabetes in humans (HR 2.9, 95% CI 2.0-4.3).

    “The highest (≥0.63) vs. lowest (<0.5, no central obesity) group of WHtR had a similar increased risk of GDM (RR 7.1, 3.9-13.2) and postpartum preDM/DM (HR 2.9, 2.0-4.3).”

    Humans≥0.63 vs. <0.5up to 9.9 yearsfemalesn = 3,055

    Central Obesity Measures in Early Pregnancy and the Risk of Gestational Diabetes (GDM) and Postpartum Prediabetes and Diabetes (preDM/DM)—A Longitudinal Cohort Study

    ADA Scientific Sessions 2025 abstract13 Jun 2025

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Body roundness index

upin humans1HR 3

1 study
  1. Body roundness index raises the risk of prediabetes and diabetes in humans (HR 3.0, 95% CI 2.0-4.4).

    “The highest (>5.9) vs. lowest (≤3.3) quartile of BRI had an increased risk of GDM (relative risk [RR] 7.5, 95% CI 4.1-13.5) and postpartum preDM/DM (hazard ratio [HR] 3.0, 2.0-4.4).”

    Humans>5.9 vs. ≤3.3up to 9.9 yearsfemalesn = 3,055

    Central Obesity Measures in Early Pregnancy and the Risk of Gestational Diabetes (GDM) and Postpartum Prediabetes and Diabetes (preDM/DM)—A Longitudinal Cohort Study

    ADA Scientific Sessions 2025 abstract13 Jun 2025

More on Body roundness index

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Endocrine

Prediabetes progression linked to later heart disease

Progression to diabetes was linked to 1.53 times the odds of later heart disease compared with consistently normal blood sugar, after accounting for other factors.Progression to diabetes was linked to 1.53 times the odds of later heart disease compared with consistently normal blood sugar, after accounting for other factors.

Cohort study of 7,927 peopleHeart disease