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Peritoneal dissemination of gastric cancer

Disease

1 paper2 findings

  • Animals1

Interventions

1

Jak/stat3 inhibitor

downin mice1

1 study

  1. Jak/stat3 inhibitor decreases peritoneal dissemination of gastric cancer in mice.

    “A JAK/STAT3 inhibitor blocks the increase in GC cell viability induced by senescent CAFs and peritoneal tumor formation.”

    Animalsinduced by senescent CAFs

    Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination

    Cell reports23 Feb 2021

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Upstream

1

JAK–STAT signalling

upin mice1

1 study

  1. JAK–STAT signalling increases peritoneal dissemination of gastric cancer in mice.

    “enhances peritoneal tumor formation of gastric cancer (GC) through JAK/STAT3 signaling in a mouse model”

    Animalsin a mouse model

    Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination

    Cell reports23 Feb 2021

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