Paravalvular leak

There are 4 papers on paravalvular leak in aging research: 1 trial and 3 observational studies in people.

4 papers study it3 more mention it1 finding

1 new paper in 30 daysSee all 7 papers on paravalvular leak

Human trial1
Humans3

Interventions

1

Tirzepatide

downin humans1

1 study

Tirzepatide decreases paravalvular leak in obese patients undergoing transfemoral TAVR (10.7% vs 25.3%; p = 0.006).
“and ≥ mild PVL (10.7% vs 25.3%, p = 0.006) at 6 months”
Human trialin obese patients undergoing transfemoral TAVR6 months
Tirzepatide therapy reduces subclinical leaflet thrombosis and paravalvular leak after transcatheter aortic valve replacement in obese patients: The TAVR-MET trial
Cardiovascular revascularization medicine : including molecular interventionsMar 23, 2026

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3 papers in 12 months

BMC Cardiovascular DisordersOct 27

Age matters? Investigating VARC-3 outcomes in surgical aortic valve reoperations: a multicenter study

Cohort study of 215 peoplePopulations

Cardiovascular Revascularization MedicineJul 4

Eyeballing versus comprehensive geriatric frailty assessment and outcomes after transcatheter aortic valve replacement: Insights from a large cohort

Cohort study of 6,343 peopleComprehensive geriatric assessment

Cardiovascular Revascularization MedicineMar 23

Tirzepatide therapy reduces subclinical leaflet thrombosis and paravalvular leak after transcatheter aortic valve replacement in obese patients: The TAVR-MET trial

Randomized trial in 260 peopleTirzepatide

Age and AgeingMar 26

Four-year clinical results of transcatheter self-expanding Medtronic CoreValve implantation in high-risk patients with severe aortic stenosis

Cohort study of 63 peopleTranscatheter aortic valve implantation

Zhejiang Da Xue Xue Bao Yi Xue BanMar 19

Impact of elevated arterial blood pressure on bioprosthetic valve calcification and failure after transcatheter aortic valve replacement

ReviewMechanisms

The Annals of Thoracic SurgerySep 28

Longitudinal Outcomes of Nonagenarians Undergoing Transcatheter Aortic Valve Replacement

Study in peopleInterventions

The American Journal of CardiologyMar 20

Early and Midterm Outcome of Propensity-Matched Intermediate-Risk Patients Aged ≥80 Years With Aortic Stenosis Undergoing Surgical or Transcatheter Aortic Valve Replacement (from the Italian Multicenter OBSERVANT Study)

Study in peopleInterventions