Metformin-associated lactic acidosis

4 papers study it4 more mention it1 finding

Interventions

1

Intensive supportive therapy

downin humans1

1 study

Intensive supportive therapy decreases metformin-associated lactic acidosis in humans (<5 mmol/l by 44 hours).
“Acidosis resolved by 36 hours after admission, and the lactate level decreased to below 5 mmol/l by 44 hours.”
Human trialsevere metformin-associated lactic acidosis36 hoursmalesn = 1
Severe Metformin-Associated Lactic Acidosis Managed Without Dialysis in an Elderly Patient With Multiple Comorbidities: A Case Report
CureusAug 9, 2025

More on Intensive supportive therapy

Trial sponsors

Humanitas Hospital, Italy
1 trialPhase 4150 people

Latest

4 papers in 12 months

CureusMar 30

Where Is the Lactate Coming From? An Unusual Presentation of Persistent Lactic Acidosis

Case reportInterventions

Therapeutic Advances in Drug SafetyMar 10

Metformin-associated lactic acidosis in an elderly diabetic patient without classical risk factors: a case report

Case reportMetformin

CureusAug 11

Severe Metformin-Associated Lactic Acidosis Managed Without Dialysis in an Elderly Patient With Multiple Comorbidities: A Case Report

Case reportInterventions

CureusJul 22

Metformin-Associated Lactic Acidosis in an Older Adult: A Case Report and Review

Case reportMechanisms

JACC Case ReportsMar 31

Pseudo-Ischemic ECG Changes in a Patient With Profound Mixed Metabolic Acidosis Due to Metformin Use

Case reportMetformin

Research SquareMar 27

Is Routine Metformin Discontinuation Necessary Before Elective Coronary Angiography? A Randomized Clinical Trial

Preprint: randomized trial in 204 peopleMetformin

Biomedicine & PharmacotherapyMar 15

Mechanism and application of metformin in kidney diseases: An update

ReviewInterventions

BMJ Case ReportsDec 21

Metformin-associated lactic acidosis precipitated by liraglutide use: adverse effects of aggressive antihyperglycaemic therapy

Interventions