Intensive supportive therapy
Intensive supportive therapy has been studied in 1 paper since 2025: none in people yet. No study of it in people or animals has been published yet. The newest paper, Aug 9, 2025: “Severe Metformin-Associated Lactic Acidosis Managed Without Dialysis in an Elderly Patient With Multiple Comorbidities: A Case Report”.
1 paper studies it1 findingUpdated
“Acidosis resolved by 36 hours after admission, and the lactate level decreased to below 5 mmol/l by 44 hours.”
- 1 lab in 1 country
What did studies of Intensive supportive therapy find?
1Studies of Intensive supportive therapy measured 1 outcome; the most studied are metformin-associated lactic acidosis (1 study).
Metformin-associated lactic acidosis
downin humans1
1 study
Metformin-associated lactic acidosis
downin humans1
Intensive supportive therapy decreases metformin-associated lactic acidosis in humans (<5 mmol/l by 44 hours).
“Acidosis resolved by 36 hours after admission, and the lactate level decreased to below 5 mmol/l by 44 hours.”
Human trialsevere metformin-associated lactic acidosis36 hoursmalesn = 1
Cureus