LATE-NC

1. MARBLE is associated with LATE-NC in humans (β = 0.083, 95% CI [0.053, 0.113]).

   Humans

   MARBLE: An in vivo MRI marker of limbic-predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-NC) · Alzheimer's & dementia : the journal of the Alzheimer's Association · 1 Sep 2026

2. MARBLE predicts LATE-NC in humans (AUC = 0.92).

   Humansante mortem intervals between MRI and death of < 3 years

   MARBLE: An in vivo MRI marker of limbic-predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-NC) · Alzheimer's & dementia : the journal of the Alzheimer's Association · 1 Sep 2026

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