Isolated growth hormone deficiency

Disease

1 paper3 findings

  • Humans1

Effects

3

IGF-2

downin humans1

1 study
  1. Isolated growth hormone deficiency decreases IGF-2 in humans (p < 0.0001).

    Humansuntreated isolated congenital GH deficiencyn = 34

    Lifelong congenital untreated isolated GH deficiency does not alter human leukocyte telomere length

    Journal of endocrinological investigation20 Aug 2026

More on IGF-2

IGF-1

downin humans1

1 study
  1. Isolated growth hormone deficiency decreases IGF-1 in humans (p < 0.0001).

    Humansuntreated isolated congenital GH deficiencyn = 34

    Lifelong congenital untreated isolated GH deficiency does not alter human leukocyte telomere length

    Journal of endocrinological investigation20 Aug 2026

More on IGF-1

Telomere length

no changein humans1

1 study
  1. Isolated growth hormone deficiency has no effect on telomere length in humans (0.96 (0.3) vs 1.01 (0.4)).

    Humansuntreated isolated congenital GH deficiencyn = 34

    Lifelong congenital untreated isolated GH deficiency does not alter human leukocyte telomere length

    Journal of endocrinological investigation20 Aug 2026

More on Telomere length

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