Incident mild cognitive impairment or dementia
Disease1 paper2 findings
- Humans1
Associations
2ADHD polygenic risk score
upin humans1HR 1.35
1 study
ADHD polygenic risk score
upin humans1HR 1.35
ADHD polygenic risk score is associated with incident mild cognitive impairment or dementia in humans (HR 1.35, 95% CI 1.25–1.46).
HumansHighest versus lowest ADHD PRS quintileMean follow-up 10.26 yearsn = 187,341
Attention-deficit/hyperactivity disorder linked to impaired thinking · JAMA psychiatry · 7 Oct 2026
Attention deficit hyperactivity disorder
upin humans1HR 4.6
1 study
Attention deficit hyperactivity disorder
upin humans1HR 4.6
Attention deficit hyperactivity disorder is associated with incident mild cognitive impairment or dementia in humans (HR 4.60, 95% CI 3.99–5.29).
HumansAdjusted Cox modelsMean follow-up 10.26 yearsn = 187,341
Attention-deficit/hyperactivity disorder linked to impaired thinking · JAMA psychiatry · 7 Oct 2026
Latest
5Attention-deficit/hyperactivity disorder linked to impaired thinking
Cognitive impairment developed in 6.7% of participants with the disorder, compared with 3.4% without it, in a cohort of adults aged 50 and older.Cognitive impairment developed in 6.7% of participants with the disorder, compared with 3.4% without it, in a cohort of adults aged 50 and older.