HTLV-1-associated myelopathy/tropical spastic paraparesis

1. HTLV-1-associated myelopathy/tropical spastic paraparesis is associated with IL-17A in humans (p = 0.0001).

   “IFN-γ (p = 0.007) and IL-17A (p = 0.0001) levels were increased in untreated HAM/TSP”

   Humansuntreated HAM/TSPplasma

   Systemic cytokines and GlycA discriminate disease status and predict corticosteroid response in HTLV-1-associated neuroinflammation

   Journal of neuroinflammation·Dec 8, 2022

2. IL-17A is associated with HTLV-1-associated myelopathy/tropical spastic paraparesis in humans (p=0.007 and p=0.0001).

   “IFN-γ (p=0.007) and IL-17A (p=0.0001) levels were increased in untreated HAM/TSP”

   Humansin untreated HAM/TSP patientsplasma

   Systemic cytokines and GlycA discriminate disease status and predict corticosteroid response in HTLV-1-associated neuroinflammation

   Research Square·Feb 17, 2022Preprint

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