CVD composite

There is 1 paper on CVD composite in aging research: 1 observational study in people. The newest story, Nov 2, 2026: “Irregular sleep linked to higher cardiovascular risk”.

Disease

1 paper studies it12 more mention it2 findings

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“Each 1-SD (29-minute) higher night-to-night variability in sleep duration was associated with higher CVD composite risk”
Sleep and Cardiometabolic Disease: A Wearable-Electronic Health Record Study in the US All of Us Research ProgramCirculation. Population health and outcomes2026doi:10.1161/circoutcomes.126.014445
  • Humans1

Interventions

1

Sleep duration

no changein humans1HR 0.96

1 study
  1. Sleep duration was not clearly linked with CVD composite in humans (HR 0.96, 95% CI 0.85–1.08).

    “mean duration was not associated with the CVD composite.”

    Humansmedian follow-up, 3.7 yearsn = 10,362

    Irregular sleep linked to higher cardiovascular risk

    Circulation. Population health and outcomes

More on Sleep duration

Associations

1

Sleep duration variability

upin humans1HR 1.24

1 study
  1. Sleep duration variability is associated with CVD composite in humans (HR 1.24, 95% CI 1.09–1.41 per 1-SD (29-minute) higher variability).

    “Each 1-SD (29-minute) higher night-to-night variability in sleep duration was associated with higher CVD composite risk”

    HumansEach 1-SD (29-minute) higher variabilitymedian follow-up, 3.7 years70% femalesn = 10,362

    Irregular sleep linked to higher cardiovascular risk

    Circulation. Population health and outcomes

More on Sleep duration variability

Latest

Dec 2025: 0Jan 2026: 1Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 1Jun 2026: 2Jul 2026: 0Aug 2026: 1Sep 2026: 2Oct 2026: 0Nov 2026: 18 papers in 12 months
Circulation Population Health and Outcomes

Irregular sleep linked to higher cardiovascular risk

Each 29-minute increase in night-to-night sleep-duration variability was linked to higher cardiovascular risk, with a hazard ratio (a relative risk measure) of 1.24.Each 29-minute increase in night-to-night sleep-duration variability was linked to higher cardiovascular risk, with a hazard ratio (a relative risk measure) of 1.24.

Cohort · 10,362 peoplePopulations

See all 13 papers on CVD composite