Clinical progression to mild cognitive impairment/dementia

Superior episodic memory is associated with clinical progression to mild cognitive impairment/dementia in humans (69%–73% reduced risk; HR 0.27–0.31, 95% CI 0.11–0.73).

“SuperAgers had 69%-73% reduced risk of clinical progression to MCI/dementia compared to CNFA”

HumansSuperAgers compared with adults cognitively normal for their age8 years

Superior Memory Reduces 8-year Risk of Mild Cognitive Impairment and Dementia But Not Amyloid β-Associated Cognitive Decline in Older Adults

Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists·Sep 11, 2018