Aggressive prostate cancer

2 papers study it7 more mention it1 finding

Humans2

Associations

1

Telomere length

upin humans1OR 2.78

1 study

Telomere length raises the risk of aggressive prostate cancer in humans (OR = 2.78; 95% CI = 1.25-6.19).
“Men in the highest telomere length quartile also had a greater risk of aggressive prostate cancer compared with men with telomere lengths in the lowest quartile (OR = 2.78; 95% CI = 1.25-6.19).”
Humanshighest vs lowest quartilemales
Race Differences in Telomere Length in Benign Prostate Biopsies and Subsequent Risk of Prostate Cancer
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive OncologyMar 3, 2022

More on Telomere length

Funding

2 grants since 2018

National Cancer InstituteUS$2m

Latest

2 papers in 12 months

European UrologyOct 23

Blood proteins linked to future prostate cancer risk

An observational study linked 12 blood proteins to prostate cancer diagnosed more than 15 years after blood collection.An observational study linked 12 blood proteins to prostate cancer diagnosed more than 15 years after blood collection.

Cohort studyProstate cancer

bioRxivJan 16

p21 CIP1/WAF1 -mediated partial senescence supports steroidogenesis and therapy resistance in primary prostate cancer cultures

Preprint: experiments in human cellsCellular senescence

Cancer Genomics & ProteomicsOct 29

Verbascoside Suppresses Epithelial-Mesenchymal Transition and Mitochondrial Biogenesis by Targeting Anti-senescence Signaling in Castration-resistant Prostate Cancer

Experiments in human cellsProstate cancer

AndrologyFeb 29

Evaluating the impact of pre-diagnostic use of statins and testosterone replacement therapy on mortality outcomes in older men with hormone-related cancers: Surveillance, Epidemiology, and End Results-Medicare 2007-2015

Study in peoplePopulations

The Journal of UrologyMay 7

Regular, Long-Duration Multivitamin Use and Risk of Overall and Aggressive Prostate Cancer in the Health Professionals Follow-Up Study

Study in peoplePopulations

Cancer Epidemiology, Biomarkers & PreventionMar 3

Race Differences in Telomere Length in Benign Prostate Biopsies and Subsequent Risk of Prostate Cancer

Case-control study in peopleTelomere length

European UrologyFeb 6

The Association Between Age, Prostate Cancer Risk, and Higher Gleason Score in a Long-term Screening Program: Results from the Göteborg-1 Prostate Cancer Screening Trial

Study in peoplePopulations

Current Oncology ReportsAug 29

Prostate Cancer in Older Adults: Risk of Clinically Meaningful Disease, the Role of Screening and Special Considerations

ReviewInterventions

British Journal of CancerSep 8

Presurgical weight loss affects tumour traits and circulating biomarkers in men with prostate cancer

Trial in peopleInterventions