Whole-brain oxygen extraction fraction

Biomarker

1 paper3 findings

  • Humans1

Associations

3

HDL

downin humans1

1 study
  1. HDL is associated with whole-brain oxygen extraction fraction in humans.

    “Whole-brain OEF was positively associated with leptin (p = 0.018) and negatively associated with HDL (p = 0.030).”

    Humansbrain

    Regional oxygen extraction fraction is higher in older adults with type 2 diabetes and obesity: associations with cognition and metabolic markers

    GeroScience13 Oct 2026

More on HDL

Leptin

upin humans1

1 study
  1. Leptin is associated with whole-brain oxygen extraction fraction in humans.

    “Whole-brain OEF was positively associated with leptin (p = 0.018) and negatively associated with HDL (p = 0.030).”

    Humansbrain

    Regional oxygen extraction fraction is higher in older adults with type 2 diabetes and obesity: associations with cognition and metabolic markers

    GeroScience13 Oct 2026

More on Leptin

Type 2 diabetes and obesity

upin humans1

1 study
  1. Type 2 diabetes and obesity is associated with whole-brain oxygen extraction fraction in humans (29.5% vs 27.3%).

    “Whole-brain OEF was higher in participants with T2D + obesity (29.5% vs 27.3%; p = 0.019)”

    Humanstype 2 diabetes and obesity versus age- and sex-matched controlsbrainn = 14

    Regional oxygen extraction fraction is higher in older adults with type 2 diabetes and obesity: associations with cognition and metabolic markers

    GeroScience13 Oct 2026

More on Type 2 diabetes and obesity

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