Regional oxygen extraction fraction

Regional oxygen extraction fraction is associated with cognitive function in humans (D-KEFS r = -0.40 to -0.62; RBANS Attention r = -0.36 to -0.41).

“Higher regional OEF significantly correlated with lower cognitive performance, particularly D-KEFS (r = -0.40 to -0.62) and RBANS Attention (r = -0.36 to -0.41).”

Humans

Regional oxygen extraction fraction is higher in older adults with type 2 diabetes and obesity: associations with cognition and metabolic markers

GeroScience·13 Oct 2026