White blood cell-to-lymphocyte ratio

1. White blood cell-to-lymphocyte ratio predicts white matter hyperintensity progression in humans (OR = 4.076).

   “In 338 patients with follow-up, baseline Q4 levels strongly predicted 3-year WMH progression (NC: OR = 4.035; NLR: OR = 5.184; WLR: OR = 4.076).”

   HumansHighest baseline quartile; progression defined as Fazekas score increase ≥ 13 yearsn = 338

   Association of peripheral blood inflammatory markers with white matter hyperintensities in the elderly

   BMC geriatrics·14 Oct 2026

1. White blood cell-to-lymphocyte ratio is associated with white matter hyperintensities in humans.

   “Adjusted for confounders, higher NC, NLR, and WLR were independently associated with WMH presence (all P < 0.05).”

   HumansHospitalized patients; adjusted for confoundersn = 428

   Association of peripheral blood inflammatory markers with white matter hyperintensities in the elderly

   BMC geriatrics·14 Oct 2026

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