Weighted 2D-kernel density estimation epigenetic clock

Weighted 2D-kernel density estimation epigenetic clock predicts chronological age in silico (R2 = 0.81; median absolute error = 4 years).

“Our weighted 2D-kernel density estimation model (WKDE) facilitated age-predictions with similar correlation and precision (R 2 = 0.81, median absolute error = 4 years)”

In silicoblood

Weighted 2D-kernel density estimations provide a new probabilistic measure for epigenetic age

bioRxiv (Cold Spring Harbor Laboratory)·11 Jun 2024Preprint