Epigenetic variation score

Epigenetic variation score is associated with mortality in humans (9.2% lower mortality risk per unit; reported 95% CI 0.8387–0.9872).

“An increase of the variation score by one unit reduced the mortality risk by 9.2% (95% CI (0.8387, 0.9872), P <0.0160)”

HumansLothian Birth Cohort 1921; adjusted for chronological age and sexbloodone-unit increase in variation score

Weighted 2D-kernel density estimations provide a new probabilistic measure for epigenetic age

bioRxiv (Cold Spring Harbor Laboratory)·11 Jun 2024Preprint