Variegated translocation mosaicism

1. Cocultivation has no effect on variegated translocation mosaicism in human cells.

   “Cocultivation of Werner's syndrome and normal strains did not induce VTM in the normal strain.”

   Cellsin normal strains

   Cytogenetics of Werner's syndrome cultured skin fibroblasts: variegated translocation mosaicism

   Cytogenetics and cell genetics·1 Jan 1981

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1. Werner syndrome increases variegated translocation mosaicism in human cells (92% vs 8.4%).

   “Ninety-two percent of 1,538 metaphases from 29 independent strains derived from five patients with Werner's syndrome demonstrated this cytogenetic abnormality.”

   Cellsin cultured skin fibroblast-like cellsn = 5

   Cytogenetics of Werner's syndrome cultured skin fibroblasts: variegated translocation mosaicism

   Cytogenetics and cell genetics·1 Jan 1981

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