UQCR10 + TNNT1 panel

Biomarker

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Sarcopenia

upin silico1

1 study
  1. UQCR10 + TNNT1 panel predicts sarcopenia in silico (AUC = 0.738 [95% CI 0.559-0.875]).

    “A two-biomarker panel (UQCR10 + TNNT1) achieved superior performance with Random Forest modeling (AUC = 0.738 [95% CI 0.559-0.875], PRAUC = 0.643 [95% CI 0.405-0.832], sensitivity = 0.850, specificity = 0.600) in the validation cohort”

    In silicoRandom Forest modeling in validation cohort (GSE111016)skeletal musclen = 40

    UQCR10 and TNNT1: novel biomarkers for sarcopenia identified through integrated transcriptomic analysis and machine learning

    European journal of medical research

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