Upper limb lean mass

1. Branched-chain amino acids have no effect on upper limb lean mass in humans (1.7 kg [-0.2; 3.6], p = 0.22).

   “or upper limb lean mass (1.7 kg [-0.2; 3.6], p = 0.22) at 12 months.”

   Human trialcirrhosis and reduced muscle strength30 g daily12 monthsn = 150

   Branched-chain amino acid supplementation does not improve measures of sarcopenia in cirrhosis: results of a randomised controlled trial

   Alimentary pharmacology & therapeutics·Feb 26, 2024

More on Branched-chain amino acids

1. Upper limb lean mass is associated with cardiovascular mortality in humans (HR 0.589, 95% CI 0.332-0.976, P = 0.041).

   “higher levels of upper limb lean mass were found to be associated with decreased cardiovascular mortality (hazard ratio, 0.589; 95% confidence interval, 0.332-0.976; P = 0.041).”

   Humansin individuals with diabetesn = 2,166

   Greater upper limb muscle mass associated with reduced cardiovascular mortality compared with other muscle groups in diabetics

   Nutrition (Burbank, Los Angeles County, Calif.)·Feb 8, 2024

1. Upper limb lean mass lowers the risk of mortality in humans (HR = 0.41, 95% CI 0.33-0.51).

   “COX regression analysis revealed that upper limbs (HR = 0.41, 95% CI 0.33-0.51), lower limbs (HR = 0.54, 95% CI 0.47-0.64), trunk (HR = 0.71, 95% CI, 0.59-0.85)”

   Humans

   Muscle distribution in relation to all-cause and cause-specific mortality in young and middle-aged adults

   Journal of translational medicine·Feb 25, 2023