Unfolded mitochondrial proteins

1 paper studies it1 more mentions it1 finding

Model organisms1

Upstream

1

Lon

downin flies1

1 study

Lon decreases unfolded mitochondrial proteins in flies.
“The translational defect of Lon KD flies was also accompanied by a substantial increase in unfolded mitochondrial proteins.”
Model organismsshown by Lon knockdown
Lon protease inactivation in Drosophila causes unfolded protein stress and inhibition of mitochondrial translation
Cell death discoveryOct 22, 2018

Latest

Cell Death DiscoveryOct 31

Lon protease inactivation in Drosophila causes unfolded protein stress and inhibition of mitochondrial translation

Experiments in fliesMitochondrion

Aging CellJun 1

Mitochondrial unfolded protein response gene Clpp is required to maintain ovarian follicular reserve during aging, for oocyte competence, and development of pre-implantation embryos

Experiments in animalsMechanisms