Transcriptional Age Deviation
1 paper3 findings
- Humans1
Associations
3Therapy resistance
upin humans1
1 study
Therapy resistance
upin humans1
Transcriptional Age Deviation is associated with therapy resistance in humans.
“Low TAD was associated with high-risk genetics and therapy resistance”
HumansLow Transcriptional Age Deviation in acute myeloid leukemia
A stem cell aging clock links biological age deviation to clinical outcome in acute myeloid leukemia
bioRxiv (Cold Spring Harbor Laboratory)13 Feb 2026Preprint
High-risk genetics
upin humans1
1 study
High-risk genetics
upin humans1
Transcriptional Age Deviation is associated with high-risk genetics in humans.
“Low TAD was associated with high-risk genetics and therapy resistance”
HumansLow Transcriptional Age Deviation in acute myeloid leukemia
A stem cell aging clock links biological age deviation to clinical outcome in acute myeloid leukemia
bioRxiv (Cold Spring Harbor Laboratory)13 Feb 2026Preprint
Survival
downin humans1
1 study
Survival
downin humans1
Transcriptional Age Deviation predicts survival in humans.
“a biologically “younger” state (low TAD), reflecting oncofetal reprogramming, is a powerful independent predictor of poor survival in two large AML cohorts.”
HumansLow Transcriptional Age Deviation in acute myeloid leukemia
A stem cell aging clock links biological age deviation to clinical outcome in acute myeloid leukemia
bioRxiv (Cold Spring Harbor Laboratory)13 Feb 2026Preprint