Total retinal pigment epithelium thickness

1. Age-related macular degeneration decreases total retinal pigment epithelium thickness in humans (P < 0.001).

   “TRPET was significantly thinner in iAMD compared with eAMD and healthy eyes (P < 0.001)”

   Humansintermediate AMD vs eAMD and healthy eyesretinan = 502

   Total Retinal Pigment Epithelium Thickness and Reflectivity, in Relation to Histology and Vision, at the Aging-AMD Transition: ALSTAR2 Baseline

   Investigative ophthalmology & visual science·1 Oct 2025

More on Age-related macular degeneration

1. Total retinal pigment epithelium thickness is associated with rod intercept time in humans (r = 0.12-0.35).

   “moderately correlated with longer RIT in all eyes (r = 0.12-0.35).”

   Humansall eyesretinan = 502

   Total Retinal Pigment Epithelium Thickness and Reflectivity, in Relation to Histology and Vision, at the Aging-AMD Transition: ALSTAR2 Baseline

   Investigative ophthalmology & visual science·1 Oct 2025