Total ghrelin

1. Weight loss increases total ghrelin in humans (SMD 0.55, 95% CI 0.07–1.04).

   “In response to weight loss induced by CR, EX or CREX, the meta-analysis revealed an increase in total ghrelin from both RCTs (SMD: 0.55, 95% CI: 0.07-1.04)”

   Reviewafter weight loss induced by calorie restriction, exercise, or both

   Fasting appetite-related gut hormone responses after weight loss induced by calorie restriction, exercise, or both in people with overweight or obesity: a meta-analysis

   International journal of obesity (2005)·Feb 10, 2025

1. Anorexia of ageing is associated with total ghrelin in humans (1333 ± 702 pg·mL−1 vs. 636 ± 251 pg·mL−1, p = 0.006).

   “total ghrelin: 1333 ± 702 pg·mL−1 vs. 636 ± 251 pg·mL−1, p = 0.006”

   Humansolder adults with low appetite vs younger adultsblood

   Anorexia of ageing is associated with elevated fasted and lower post-prandial ghrelin, independent of ghrelin O-acyltransferase

   Appetite·Feb 8, 2024

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