NPJ Parkinson's Disease
Some blood amino acids linked to lower Parkinson’s risk
A prospective cohort study of 374,751 UK Biobank participants linked higher levels of certain protein building blocks to a lower risk of developing Parkinson’s disease.A prospective cohort study of 374,751 UK Biobank participants linked higher levels of certain protein building blocks to a lower risk of developing Parkinson’s disease.
Cohort · 374,751 peopleParkinson's disease
Who was studied374,751 UK Biobank participants without neurodegenerative diseases
What changedHigher blood levels of total branched-chain amino acids, leucine, and valine were linked to lower Parkinson’s disease risk
The catchParkinson’s changes before diagnosis may alter amino acid levels, reversing the apparent causal direction