Total arterial compliance

1. Total arterial compliance has no effect on baroreflex sensitivity in humans (No significant association; both p > 0.05).

   “TAC was not associated with BRS during either orthostatic transition (both p > 0.05).”

   HumansDuring sitting-to-standing and lying-to-standing transitions

   Reduced total arterial compliance in frail older adults is associated with orthostatic blood pressure variability but not baroreflex sensitivity

   The Journal of frailty & aging·13 Oct 2026

More on Baroreflex sensitivity

1. Total arterial compliance is associated with systolic blood pressure variability in humans (VLF: β = -0.60, p < 0.001; LF: β = -0.56, p < 0.001; HF: β = -0.32, p = 0.04).

   “lying-to-standing (SBPV-VLF: β = -0.60, p < 0.001; SBPV-LF: β = -0.56, p < 0.001; SBPV-HF: β = -0.32, p = 0.04).”

   HumansLying-to-standing transition; adjusted for frailty status and medication use

   Reduced total arterial compliance in frail older adults is associated with orthostatic blood pressure variability but not baroreflex sensitivity

   The Journal of frailty & aging·13 Oct 2026

More on Systolic blood pressure variability

1. Total arterial compliance is associated with very-low-frequency systolic blood pressure variability in humans (β = -0.46, p = 0.006).

   “lower TAC was associated with greater systolic BPV during sitting-to-standing (SBPV-VLF: β = -0.46, p = 0.006)”

   HumansSitting-to-standing transition; adjusted for frailty status and medication use

   Reduced total arterial compliance in frail older adults is associated with orthostatic blood pressure variability but not baroreflex sensitivity

   The Journal of frailty & aging·13 Oct 2026

More on Very-low-frequency systolic blood pressure variability

1. Frailty is associated with total arterial compliance in humans.

   “Frail participants exhibited lower TAC than non-frail participants during both conditions (all p < 0.05).”

   HumansDuring sitting-to-standing and lying-to-standing transitions; frail versus non-frail participants

   Reduced total arterial compliance in frail older adults is associated with orthostatic blood pressure variability but not baroreflex sensitivity

   The Journal of frailty & aging·13 Oct 2026