Time-to-amyloid-positivity

1. Plasma pTau217 is associated with time-to-amyloid-positivity in humans (MAE = 5.2 years, ρ = 0.226).

   “At lower cortical amyloid levels (< 30 CL), plasma pTau217 was highly variable (MAE = 5.2 years, ρ = 0.226).”

   Humanscortical amyloid levels < 30 CL

   Plasma pTau217 as a marker of both the current and future state of amyloid pathology in adults with DS

   AAIC 2025 abstract·25 Dec 2025

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