Time from amyloid positivity
1 paper2 findings
- Humans1
Associations
2Cognitive function
upin humans1+19% variance explained
1 study
Cognitive function
upin humans1+19% variance explained
Time from amyloid positivity is associated with cognitive function in humans (19% of variance explained).
“A time explained 19% of the variance in the general cognitive composite while EYO explained 43% of the variance.”
Humansn = 316
Validation of Amyloid Chronicity in Autosomal Dominant Alzheimer Disease
AAIC 2025 abstract25 Dec 2025
Estimated age at symptom onset
upin humans1
1 study
Estimated age at symptom onset
upin humans1
Time from amyloid positivity predicts estimated age at symptom onset in humans.
“Across all participants, SILA‐estimated age at A+ explained 39% of the variance in estimated age at symptom onset ( β = 0.918, p < 0.0001).”
Humansn = 316
Validation of Amyloid Chronicity in Autosomal Dominant Alzheimer Disease
AAIC 2025 abstract25 Dec 2025
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3 in 12 monthsJournal of the American Geriatrics Society
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AAIC 2025 Abstract
Validation of Amyloid Chronicity in Autosomal Dominant Alzheimer Disease
Cohort study of 316 peopleAlzheimer's disease
AAIC 2025 Abstract
Plasma pTau217 as a marker of both the current and future state of amyloid pathology in adults with DS
Cohort study of 329 peoplepTau217