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Testosterone/estradiol ratio

Biomarker

2 findings

Associations

2

DNAm PAI-1

downin humans1

1 study

  1. Testosterone/estradiol ratio is associated with DNAm PAI-1 in humans (-351 pg/mL (95% CI -486 to -217)).

    “and DNAm PAI1 (-351 pg/mL; 95%CI: -486 to -217; P:4e-7; BH-P:3e-6) among men.”

    Humansmales

    Higher testosterone and testosterone/estradiol ratio in men are associated with decreased Pheno-/GrimAge and DNA-methylation based PAI1

    GeroScience27 Jun 2023

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PhenoAge

downin humans1

1 study

  1. Testosterone/estradiol ratio is associated with PhenoAge in humans (-0.41 years (95% CI -0.70 to -0.12)).

    “The testosterone/estradiol (TE) ratio was associated with a decrease in Pheno AA (-0.41 years; 95%CI: -0.70 to -0.12; P:0.01; BH-P: 0.04)”

    Humansmales

    Higher testosterone and testosterone/estradiol ratio in men are associated with decreased Pheno-/GrimAge and DNA-methylation based PAI1

    GeroScience27 Jun 2023

More on PhenoAge

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