Tau inclusions

2 papers study it6 more mention it1 finding

Animals1
Model organisms1

Upstream

1

Human kinases

upin worms1

1 study

human kinases induce tau inclusions in worms.
“Kinase expression additionally induced tau inclusions in a small proportion of animals.”
Model organismshuman kinase co-expression with human tau
Human tau compromises neuronal structural integrity in C. elegans promoted by age, stress and phosphorylation
bioRxiv (Cold Spring Harbor Laboratory)Aug 1, 2025Preprint

Latest

bioRxivAug 1

Human tau compromises neuronal structural integrity in C. elegans promoted by age, stress and phosphorylation

Preprint: experiments in wormsMechanisms

Nature MetabolismJul 1

Neuronal glycogen breakdown mitigates tauopathy via pentose-phosphate-pathway-mediated oxidative stress reduction

Study in peopleOxidative stress and ROS signaling

Cell Death & DiseaseJul 31

Anti-tau single domain antibodies clear pathological tau and attenuate its toxicity and related functional defects

Experiments in fliesInterventions

The Journal of Biological ChemistrySep 5

Spreading of Alzheimer tau seeds is enhanced by aging and template matching with limited impact of amyloid-β

Experiments in animalsMechanisms

BrainMay 12

Tau immunophenotypes in chronic traumatic encephalopathy recapitulate those of ageing and Alzheimer's disease

Study in peopleMechanisms

Neurobiology of AgingJul 16

A 4R tauopathy develops without amyloid deposits in aged cat brains

Experiments in animalsMechanisms

NeuronFeb 1

Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

Experiments in miceSynapse

The Journal of NeuroscienceMay 12

Retarded axonal transport of R406W mutant tau in transgenic mice with a neurodegenerative tauopathy

Experiments in miceMechanisms