TAD boundary integrity

1 paper1 finding

Cells1

Associations

1

Hematopoietic stem cell ageing

downin mice1

1 study

Hematopoietic stem cell ageing is associated with TAD boundary integrity in mice.
“Aged HSCs display erosion of topologically associating domain (TAD) boundaries”
Animalshematopoietic stem cell
Multi-omic gene regulatory networks informed by 3D chromatin architecture reveal insights into hematopoietic stem cell ageing
bioRxiv (Cold Spring Harbor Laboratory)22 Apr 2026Preprint

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bioRxiv22 Apr

Multi-omic gene regulatory networks informed by 3D chromatin architecture reveal insights into hematopoietic stem cell ageing

Preprint: experiments in mouse cellsChromatin and 3D genome organisation