What does the research say about Synaptic and neurosecretory protein signature?

Synaptic and neurosecretory protein signature

There is 1 paper on synaptic and neurosecretory protein signature in aging research: 1 observational study in people. The newest story, Oct 20, 2026: “Spinal fluid protein patterns recur in early Parkinson’s”.

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“A reproducible set of synaptic and neurosecretory proteins separated controls from Stage 3 (RPH3A, STX1B, NRXN1, PALM, NPY).”

Reproducible cerebrospinal fluid proteomic signatures across early neuronal α-synuclein disease stages in PPMImedRxiv2026doi:10.64898/2026.10.18.26365832

Humans1

Associations

Neuronal α-synuclein disease

mixedin humans1

1 study

Neuronal α-synuclein disease is associated with synaptic and neurosecretory protein signature in humans (Stage 3 versus healthy controls).
“A reproducible set of synaptic and neurosecretory proteins separated controls from Stage 3 (RPH3A, STX1B, NRXN1, PALM, NPY).”
HumansStage 3 versus healthy controlscerebrospinal fluid
Spinal fluid protein patterns recur in early Parkinson’s
medRxivOct 20, 2026Preprint

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1 paper in 12 months

medRxivOct 20

Spinal fluid protein patterns recur in early Parkinson’s

The observational preprint compared healthy controls, people with possible early signs and people with untreated Parkinson’s in independent cohorts of 721 and 974…The observational preprint compared healthy controls, people with possible early signs and people with untreated Parkinson’s in independent cohorts of 721 and 974 participants.

Preprint: cross-sectional studyParkinson's disease

Paper

Synaptic and neurosecretory protein signature

Associations

Latest

Spinal fluid protein patterns recur in early Parkinson’s

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